RAPID COMMUNICATION Detection of Human T-cell Leukemia/Lymphoma Virus, Type 11, in a Patient With Large Granular Lymphocyte Leukemia

نویسندگان

  • Thomas P. Loughran
  • Thomas Coyle
  • Michael P. Sherman
  • Gordon Starkebaum
  • Garth D. Ehrlich
  • Francis W. Ruscetti
چکیده

We studied a patient with large granular lymphocyte (LGL) leukemia for evidence of human T-cell leukemia/lymphoma virus (HTLV) infection. Serum from this patient was positive for HTLV-I/ II antibodies by enzyme-linked immunosorbent assay (ELISA) and was confirmed positive in Western blot and radioimmunoprecipitation assays. Results of a synthetic peptide-based ELISA showed that the seropositivity was caused by HTLV-II and not HTLV-I infection. Analyses of enzymatic amplification of DNA from bone marrow sections

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Detection of Human T - cell Leukemia / Lymphoma Virus , Type 11 , in a Patient With Large Granular Lymphocyte Leukemia

We studied a patient with large granular lymphocyte (LGL) leukemia for evidence of human T-cell leukemia/lymphoma virus (HTLV) infection. Serum from this patient was positive for HTLV-I/ II antibodies by enzyme-linked immunosorbent assay (ELISA) and was confirmed positive in Western blot and radioimmunoprecipitation assays. Results of a synthetic peptide-based ELISA showed that the seropositivi...

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تاریخ انتشار 2003